RESEARCH GROUPS
Systems Neuroscience

ABOUT

Systems Neuroscience

Mainen Lab

We do not perceive the world directly. Rather, our brains must decipher what is out there using the window of information we receive from our senses. The result of this process is referred to as a ‘model’ of the world. Understanding how brains construct and use internal models is a central problem in neuroscience. This problem can be approached by thinking of the brain as a kind of an intuitive scientist, collecting and analysing data, constructing and testing hypotheses based on those data, and revising them in light of new data. Each brain gets different data and produces a different model, making the beliefs that guide our actions subjective and sometimes wrong. Fortunately, like a good scientist, our brains can and do evaluate the quality of the data. This gives us a sense of confidence in our beliefs and decisions, helping us to know when our subjective reality is worth acting on and when to question it. Understanding how all this works in terms of neural circuits is the long-term goal of research in the Systems Neuroscience lab. 

Info

Main Interests

How brains use perceptual information to create and act on models of the world, the role of confidence, uncertainty and neuromodulators in these processes

Methods

Optogenetics, Theory, Behaviour, Electrophysiology

Models and Regions

Rats, Mice, Humans / Cortex and Raphe Nuclei

Opportunities

If you are interested in joining our group, please contact Zachary Mainen at the email address bellow.

zmainen@neuro.fchampalimaud.org

Lab Webpage

mainenlab.org

PROJECTS

Systems Neuroscience

TEAM

Systems Neuroscience

Know our Team

Zachary Mainen

Zachary Mainen, PhD

Principal Investigator

Madalena Fonseca

Madalena Fonseca

2013 INDP PhD Student

Pietro Vertechi

Pietro Vertechi

2014 INDP PhD Student

Dario Sarra

Dario Sarra

2016 INDP PhD Student

Kcénia Bougrova

Kcénia Bougrova

2017 INDP PhD Student

Solène Sautory

Solène Sautory

2017 INDP PhD Student

Tiago Quendera

Tiago Quendera

2017 INDP PhD Student

Catarina Pimentel

Catarina Pimentel, PhD

Lab Manager

João Morais

João Morais

Masters Student

Lucas Soares

Lucas Soares

Masters Student

Cindy Poo

Cindy Poo, PhD

Postdoctoral Researcher

Eric Dewitt

Eric Dewitt, PhD

Postdoctoral Researcher

Fanny Cazettes

Fanny Cazettes, PhD

Postdoctoral Researcher

Gautam Agarwal

Gautam Agarwal, PhD

Postdoctoral Researcher

Guido Meijer

Guido Meijer, PhD

Postdoctoral Researcher

Hanne Stensola

Hanne Stensola, PhD

Postdoctoral Researcher

Julia Huntenburg

Julia Huntenburg, PhD

Postdoctoral Researcher

Mattia Bergomi

Mattia Bergomi, PhD

Postdoctoral Researcher

Niccolò Bonacchi

Niccolò Bonacchi, PhD

Postdoctoral Researcher

Romain Ligneul

Romain Ligneul, PhD

Postdoctoral Researcher

Tor Stensola

Tor Stensola, PhD

Postdoctoral Researcher

Beatriz Godinho

Beatriz Godinho

Research Assistant

Inês Laranjeira

Inês Laranjeira

Research Technician

José Miguel Teixeira

José Miguel Teixeira

Research Technician

Margarida Duarte

Margarida Duarte, PhD

Research Technician

Megha Patwa

Megha Patwa

Research Technician

Olivier Winter

Olivier Winter

Senior Technician

Eleni Smaragdi

Eleni Smaragdi

Technician

Margarida Nunes

Margarida Nunes

Lab Administrator

PUBLICATIONS

Know our Publications