18 Sep 2019

How sleepless nights compromise the health of your gut

Why are individuals that have irregular schedules more susceptible to gut inflammation and obesity? A study by the Immunophysiology group reveals a link between gut immune function and the brain’s circadian clock may very well be the answer.

How sleepless nights compromise the health of your gut

It is well known that individuals who work night-shifts, or travel often across different time zones, have a higher tendency to become overweight and suffer from gut inflammation. The underlying cause for this robust phenomenon has been the subject of many studies that tried to relate physiological processes with the activity of the brain’s circadian clock, which is generated in response to the daylight cycle.

Now, the group of Henrique Veiga-Fernandes, at the Champalimaud Centre for the Unknown in Lisbon, Portugal, discovered that the function of a group of immune cells, which are known to be strong contributors to gut health, is directly controlled by the brain’s circadian clock. Their findings were published today in the scientific journal Nature.

Read the full story here.