Publications 2018 - to date

Jeremiah C, Petersen E, Nantanda R, Mungai BN, Migliori GB, Amanullah F, Lungu P, Ntoumi F, Kumarasamy N, Maeurer M, Zumla A. The WHO Global Tuberculosis 2021 Report – not so good news and turning the tide back to End TB. Int J Infect Dis. 2022 Mar 20:S1201-9712(22)00149-7. doi: 10.1016/j.ijid.2022.03.011. Epub ahead of print. PMID: 35321845; PMCID: PMC8934249.

Ntoumi F, Petersen E, Mwaba P, Aklillu E, Mfinanga S, Yeboah-Manu D, Maeurer M, Zumla A. Blue Skies research is essential for ending the Tuberculosis pandemic and advancing a personalized medicine approach for holistic management of Respiratory Tract infections. Int J Infect Dis. 2022 Mar 14:S1201-9712(22)00150-3. doi: 10.1016/j.ijid.2022.03.012. Epub ahead of print. PMID: 35301102; PMCID: PMC8920086.

Petersen E, Al-Abri S, Chakaya J, Goletti D, Parolina L, Wejse C, Mucheleng’anga LA, Khalili SA, Yeboah-Manu D, Chanda-Kapata P, Nasiri MJ, Lungu PS, Maeurer M, Tiberi S, Ntoumi F, Battista-Migliori G, Zumla A. World TB Day 2022: Revamping and Reshaping Global TB Control Programs by Advancing Lessons learnt from the COVID-19 pandemic. Int J Infect Dis. 2022 Mar 4:S1201-9712(22)00138-2. doi: 10.1016/j.ijid.2022.02.057. Epub ahead of print. PMID: 35248715; PMCID: PMC8894685.

Fahrner JE, Lahmar I, Goubet AG, Haddad Y, Carrier A, Mazzenga M, Drubay D, Alves Costa Silva C; Lyon COVID Study Group, de Sousa E, Thelemaque C, Melenotte C, Dubuisson A, Geraud A, Ferrere G, Birebent R, Bigenwald C, Picard M, Cerbone L, Lérias JR, Laparra A, Bernard-Tessier A, Kloeckner B, Gazzano M, Danlos FX, Terrisse S, Pizzato E, Flament C, Ly P, Tartour E, Benhamouda N, Meziani L, Ahmed-Belkacem A, Miyara M, Gorochov G, Barlesi F, Trubert A, Ungar B, Estrada Y, Pradon C, Gallois E, Pommeret F, Colomba E, Lavaud P, Deloger M, Droin N, Deutsch E, Gachot B, Spano JP, Merad M, Scotté F, Marabelle A, Griscelli F, Blay JY, Soria JC, Merad M, André F, Villemonteix J, Chevalier MF, Caillat-Zucman S, Fenollar F, Guttman-Yassky E, Launay O, Kroemer G, La Scola B, Maeurer M, Derosa L, Zitvogel L. The Polarity and Specificity of Antiviral T Lymphocyte Responses Determine Susceptibility to SARS-CoV-2 Infection in Patients with Cancer and Healthy Individuals. Cancer Discov. 2022 Apr 1;12(4):958-983. doi: 10.1158/2159-8290.CD-21-1441. PMID: 35179201.

Petersen E, Ntoumi F, Hui DS, Abubakar A, Kramer LD, Obiero C, Tambyah PA, Blumberg L, Yapi R, Al-Abri S, Pinto TCA, Yeboah-Manu D, Haider N, Asogun D, Velavan TP, Kapata N, Bates M, Ansumana R, Montaldo C, Mucheleng’anga L, Tembo J, Mwaba P, Himwaze CM, Hamid MMA, Mfinanga S, Mboera L, Raj T, Aklillu E, Veas F, Edwards S, Kaleebu P, McHugh TD, Chakaya J, Nyirenda T, Bockarie M, Nyasulu PS, Wejse C, Muyembe-Tamfum JJ, Azhar EI, Maeurer M, Nachega JB, Kock R, Ippolito G, Zumla A. Emergence of new SARS-CoV-2 Variant of Concern Omicron (B.1.1.529) – highlights Africa’s research capabilities, but exposes major knowledge gaps, inequities of vaccine distribution, inadequacies in global COVID-19 response and control efforts. Int J Infect Dis. 2022 Jan;114:268-272. doi: 10.1016/j.ijid.2021.11.040. Epub 2021 Dec 1. PMID: 34863925; PMCID: PMC8634699.

Lanini S, Capone S, Antinori A, Milleri S, Nicastri E, Camerini R, Agrati C, Castilletti C, Mori F, Sacchi A, Matusali G, Gagliardini R, Ammendola V, Cimini E, Grazioli F, Scorzolini L, Napolitano F, Plazzi MM, Soriani M, De Luca A, Battella S, Sommella A, Contino AM, Barra F, Gentile M, Raggioli A, Shi Y, Girardi E, Maeurer M, Capobianchi MR, Vaia F, Piacentini M, Kroemer G, Vitelli A, Colloca S, Folgori A, Ippolito G. GRAd-COV2, a gorilla adenovirus-based candidate vaccine against COVID-19, is safe and immunogenic in younger and older adults. Sci Transl Med. 2022 Jan 12;14(627):eabj1996. doi: 10.1126/scitranslmed.abj1996. Epub 2022 Jan 12. PMID: 34698501.

Singh J, Alam A, Samal J, Maeurer M, Ehtesham NZ, Chakaya J, Hira S, Hasnain SE. Role of multiple factors likely contributing to severity-mortality of COVID-19. Infect Genet Evol. 2021 Dec;96:105101. doi: 10.1016/j.meegid.2021.105101. Epub 2021 Oct 5. PMID: 34624542; PMCID: PMC8491954.

Shaw TD, Krasnodembskaya AD, Schroeder GN, Zumla A, Maeurer M, O’Kane CM. Mesenchymal Stromal Cells: an Antimicrobial and Host-Directed Therapy for Complex Infectious Diseases. Clin Microbiol Rev. 2021 Dec 15;34(4):e0006421. doi: 10.1128/CMR.00064-21. Epub 2021 Oct 6. PMID: 34612662; PMCID: PMC8510528.

Messina F, Giombini E, Montaldo C, Sharma AA, Zoccoli A, Sekaly RP, Locatelli F, Zumla A, Maeurer M, Capobianchi MR, Lauria FN, Ippolito G. Looking for pathways related to COVID-19: confirmation of pathogenic mechanisms by SARS- CoV-2-host interactome. Cell Death Dis. 2021 Aug 12;12(8):788. doi: 10.1038/s41419-021-03881-8. PMID: 34385425; PMCID: PMC8357963.

de Sousa E, Lérias JR, Beltran A, Paraschoudi G, Condeço C, Kamiki J, António PA, Figueiredo N, Carvalho C, Castillo-Martin M, Wang Z, Ligeiro D, Rao M, Maeurer M. Targeting Neoepitopes to Treat Solid Malignancies: Immunosurgery. Front Immunol. 2021 Jul 15;12:592031. doi: 10.3389/fimmu.2021.592031. PMID: 34335558; PMCID: PMC8320363.

Goubet AG, Dubuisson A, Geraud A, Danlos FX, Terrisse S, Silva CAC, Drubay D, Touri L, Picard M, Mazzenga M, Silvin A, Dunsmore G, Haddad Y, Pizzato E, Ly P, Flament C, Melenotte C, Solary E, Fontenay M, Garcia G, Balleyguier C, Lassau N, Maeurer M, Grajeda-Iglesias C, Nirmalathasan N, Aprahamian F, Durand S, Kepp O, Ferrere G, Thelemaque C, Lahmar I, Fahrner JE, Meziani L, Ahmed-Belkacem A, Saïdani N, La Scola B, Raoult D, Gentile S, Cortaredona S, Ippolito G, Lelouvier B, Roulet A, Andre F, Barlesi F, Soria JC, Pradon C, Gallois E, Pommeret F, Colomba E, Ginhoux F, Kazandjian S, Elkrief A, Routy B, Miyara M, Gorochov G, Deutsch E, Albiges L, Stoclin A, Gachot B, Florin A, Merad M, Scotte F, Assaad S, Kroemer G, Blay JY, Marabelle A, Griscelli F, Zitvogel L, Derosa L. Prolonged SARS-CoV-2 RNA virus shedding and lymphopenia are hallmarks of COVID-19 in cancer patients with poor prognosis. Cell Death Differ. 2021 Dec;28(12):3297-3315. doi: 10.1038/s41418-021-00817-9. Epub 2021 Jul 6. PMID: 34230615; PMCID: PMC8259103.

Nachega JB, Maeurer M, Sam-Agudu NA, Chakaya J, Katoto PDM, Zumla A. Bacille Calmette-Guérin (BCG) vaccine and potential cross-protection against SARS-CoV-2 infection – Assumptions, knowns, unknowns and need for developing an accurate scientific evidence base. Int J Infect Dis. 2021 Dec;113 Suppl 1:S78-S81. doi: 10.1016/j.ijid.2021.03.060. Epub 2021 Mar 29. PMID: 33794380; PMCID: PMC8006492.

Zumla A, Chakaya J, Khan M, Fatima R, Wejse C, Al-Abri S, Fox GJ, Nachega J, Kapata N, Knipper M, Orcutt M, Goscé L, Abubakar I, Nagu TJ, Mugusi F, Gordon AK, Shanmugam S, Bachmann NL, Lam C, Sintchenko V, Rudolf F, Amanullah F, Kock R, Haider N, Lipman M, King M, Maeurer M, Goletti D, Petrone L, Yaqoob A, Tiberi S, Ditiu L, Sahu S, Marais B, Issayeva AM, Petersen E. World Tuberculosis Day 2021 Theme – ‘The Clock is Ticking’ – and the world is running out of time to deliver the United Nations General Assembly commitments to End TB due to the COVID-19 pandemic. Int J Infect Dis. 2021 Dec;113 Suppl 1:S1-S6. doi: 10.1016/j.ijid.2021.03.046. Epub 2021 Mar 18. PMID: 33746094.

Nagu TJ, Mboka MA, Nkrumbih ZF, Shayo G, Mizinduko MM, Komba EV, Maeurer M, Zumla A, Mugusi F. Clinical and Imaging Features of Adults with Recurrent Pulmonary Tuberculosis – A Prospective Case-Controlled Study. Int J Infect Dis. 2021 Dec;113 Suppl 1:S33-S39. doi: 10.1016/j.ijid.2021.01.071. Epub 2021 Mar 11. PMID: 33716197.

Maeurer M, Ramalho R, Wang FS, Zumla A. Host-directed therapies for COVID-19. Curr Opin Pulm Med. 2021 May 1;27(3):205-209. doi: 10.1097/MCP.0000000000000769. PMID: 33629969.

Bordoni V, Tartaglia E, Sacchi A, Fimia GM, Cimini E, Casetti R, Notari S, Grassi G, Marchioni L, Bibas M, Capobianchi MR, Locatelli F, Maeurer M, Zumla A, Antinori A, Nicastri E, Ippolito G, Agrati C. The unbalanced p53/SIRT1 axis may impact lymphocyte homeostasis in COVID-19 patients. Int J Infect Dis. 2021 Apr;105:49-53. doi: 10.1016/j.ijid.2021.02.019. Epub 2021 Feb 10. PMID: 33578018; PMCID: PMC7872850.

Shi L, Huang H, Lu X, Yan X, Jiang X, Xu R, Wang S, Zhang C, Yuan X, Xu Z, Huang L, Fu JL, Li Y, Zhang Y, Yao WQ, Liu T, Song J, Sun L, Yang F, Zhang X, Zhang B, Shi M, Meng F, Song Y, Yu Y, Wen J, Li Q, Mao Q, Maeurer M, Zumla A, Yao C, Xie WF, Wang FS. Effect of human umbilical cord-derived mesenchymal stem cells on lung damage in severe COVID-19 patients: a randomized, double-blind, placebo-controlled phase 2 trial. Signal Transduct Target Ther. 2021 Feb 10;6(1):58. doi: 10.1038/s41392-021-00488-5. PMID: 33568628; PMCID: PMC7873662.

Carsetti R, Zaffina S, Piano Mortari E, Terreri S, Corrente F, Capponi C, Palomba P, Mirabella M, Cascioli S, Palange P, Cuccaro I, Milito C, Zumla A, Maeurer M, Camisa V, Vinci MR, Santoro A, Cimini E, Marchioni L, Nicastri E, Palmieri F, Agrati C, Ippolito G, Porzio O, Concato C, Onetti Muda A, Raponi M, Quintarelli C, Quinti I, Locatelli F. Different Innate and Adaptive Immune Responses to SARS-CoV-2 Infection of Asymptomatic, Mild, and Severe Cases. Front Immunol. 2020 Dec 16;11:610300. doi: 10.3389/fimmu.2020.610300. PMID: 33391280; PMCID: PMC7772470.

Lanini S, Montaldo C, Nicastri E, Vairo F, Agrati C, Petrosillo N, Scognamiglio P, Antinori A, Puro V, Di Caro A, De Carli G, Navarra A, Agresta A, Cimaglia C, Palmieri F, D’Offizi G, Marchioni L, Kobinger GP, Maeurer M, Girardi E, Capobianchi MR, Zumla A, Locatelli F, Ippolito G. COVID-19 disease-Temporal analyses of complete blood count parameters over course of illness, and relationship to patient demographics and management outcomes in survivors and non-survivors: A longitudinal descriptive cohort study. PLoS One. 2020 Dec 28;15(12):e0244129. doi: 10.1371/journal.pone.0244129. PMID: 33370366; PMCID: PMC7769441.

Ippolito G, Lauria FN, Locatelli F, Magrini N, Montaldo C, Sadun R, Maeurer M, Strada G, Vairo F, Curiale S, Lafont A, di Caro A, Capobianchi MR, Meilicke R, Petersen E, Zumla A, Pletschette M. Lessons from the COVID-19 Pandemic-Unique Opportunities for Unifying, Revamping and Reshaping Epidemic Preparedness of Europe’s Public Health Systems. Int J Infect Dis. 2020 Dec;101:361-366. doi: 10.1016/j.ijid.2020.10.094. Epub 2020 Nov 2. PMID: 33152511.

Ligeiro D, Rao M, Maia A, Castillo M, Beltran A, Maeurer M. B Cells in the Gastrointestinal Tumor Microenvironment with a Focus on Pancreatic Cancer: Opportunities for Precision Medicine? Adv Exp Med Biol. 2020;1273:175-195. doi: 10.1007/978-3-030-49270-0_10. PMID: 33119882.

Sacchi A, Grassi G, Bordoni V, Lorenzini P, Cimini E, Casetti R, Tartaglia E, Marchioni L, Petrosillo N, Palmieri F, D’Offizi G, Notari S, Tempestilli M, Capobianchi MR, Nicastri E, Maeurer M, Zumla A, Locatelli F, Antinori A, Ippolito G, Agrati C. Early expansion of myeloid-derived suppressor cells inhibits SARS-CoV-2 specific T-cell response and may predict fatal COVID-19 outcome. Cell Death Dis. 2020 Oct 27;11(10):921. doi: 10.1038/s41419-020-03125-1. PMID: 33110074; PMCID: PMC7590570.

Mondi A, Cimini E, Colavita F, Cicalini S, Pinnetti C, Matusali G, Casetti R, Maeurer M, Vergori A, Mazzotta V, Gagliardini R, De Zottis F, Schininà V, Girardi E, Puro V, Ippolito G, Vaia F, Capobianchi MR, Castilletti C, Agrati C, Antinori A. COVID-19 in people living with HIV: Clinical implications of dynamics of the immune response to SARS-CoV-2. J Med Virol. 2021 Mar;93(3):1796-1804. doi: 10.1002/jmv.26556. Epub 2020 Oct 8. PMID: 32975842; PMCID: PMC7537181.

Melenotte C, Silvin A, Goubet AG, Lahmar I, Dubuisson A, Zumla A, Raoult D, Merad M, Gachot B, Hénon C, Solary E, Fontenay M, André F, Maeurer M, Ippolito G, Piacentini M, Wang FS, Ginhoux F, Marabelle A, Kroemer G, Derosa L, Zitvogel L. Immune responses during COVID-19 infection. Oncoimmunology. 2020 Aug 25;9(1):1807836. doi: 10.1080/2162402×.2020.1807836. PMID: 32939324; PMCID: PMC7480812.

Zumla A, Marais BJ, McHugh TD, Maeurer M, Zumla A, Kapata N, Ntoumi F, Chanda-Kapata P, Mfinanga S, Centis R, Cirillo DM, Petersen E, Hui DS, Ippolito G, Leung CC, Migliori GB, Tiberi S. COVID-19 and tuberculosis-threats and opportunities. Int J Tuberc Lung Dis. 2020 Aug 1;24(8):757-760. doi: 10.5588/ijtld.20.0387. PMID: 32912377.

Meng F, Xu R, Wang S, Xu Z, Zhang C, Li Y, Yang T, Shi L, Fu J, Jiang T, Huang L, Zhao P, Yuan X, Fan X, Zhang JY, Song J, Zhang D, Jiao Y, Liu L, Zhou C, Maeurer M, Zumla A, Shi M, Wang FS. Human umbilical cord-derived mesenchymal stem cell therapy in patients with COVID-19: a phase 1 clinical trial. Signal Transduct Target Ther. 2020 Aug 27;5(1):172. doi: 10.1038/s41392-020-00286-5. PMID: 32855385; PMCID: PMC7450163.

Zhang JY, Wang XM, Xing X, Xu Z, Zhang C, Song JW, Fan X, Xia P, Fu JL, Wang SY, Xu RN, Dai XP, Shi L, Huang L, Jiang TJ, Shi M, Zhang Y, Zumla A, Maeurer M, Bai F, Wang FS. Single-cell landscape of immunological responses in patients with COVID-19. Nat Immunol. 2020 Sep;21(9):1107-1118. doi: 10.1038/s41590-020-0762-x. Epub 2020 Aug 12. PMID: 32788748.

de Sousa E, Ligeiro D, Lérias JR, Zhang C, Agrati C, Osman M, El-Kafrawy SA, Azhar EI, Ippolito G, Wang FS, Zumla A, Maeurer M. Mortality in COVID-19 disease patients: Correlating the association of major histocompatibility complex (MHC) with severe acute respiratory syndrome 2 (SARS-CoV-2) variants. Int J Infect Dis. 2020 Sep;98:454-459. doi: 10.1016/j.ijid.2020.07.016. Epub 2020 Jul 18. PMID: 32693089; PMCID: PMC7368421.

Song JW, Zhang C, Fan X, Meng FP, Xu Z, Xia P, Cao WJ, Yang T, Dai XP, Wang SY, Xu RN, Jiang TJ, Li WG, Zhang DW, Zhao P, Shi M, Agrati C, Ippolito G, Maeurer M, Zumla A, Wang FS, Zhang JY. Immunological and inflammatory profiles in mild and severe cases of COVID-19. Nat Commun. 2020 Jul 8;11(1):3410. doi: 10.1038/s41467-020-17240-2. PMID: 32641700; PMCID: PMC7343781.

Messina F, Giombini E, Agrati C, Vairo F, Ascoli Bartoli T, Al Moghazi S, Piacentini M, Locatelli F, Kobinger G, Maeurer M, Zumla A, Capobianchi MR, Lauria FN, Ippolito G; COVID 19 INMI Network Medicine for IDs Study Group. COVID-19: viral-host interactome analyzed by network based-approach model to study pathogenesis of SARS-CoV-2 infection. J Transl Med. 2020 Jun 10;18(1):233. doi: 10.1186/s12967-020-02405-w. PMID: 32522207; PMCID: PMC7286221.

Ramalho R, Rao M, Zhang C, Agrati C, Ippolito G, Wang FS, Zumla A, Maeurer M. Immunometabolism: new insights and lessons from antigen-directed cellular immune responses. Semin Immunopathol. 2020 Jun;42(3):279-313. doi: 10.1007/s00281-020-00798-w. Epub 2020 Jun 9. PMID: 32519148; PMCID: PMC7282544.

Agrati C, Sacchi A, Bordoni V, Cimini E, Notari S, Grassi G, Casetti R, Tartaglia E, Lalle E, D’Abramo A, Castilletti C, Marchioni L, Shi Y, Mariano A, Song JW, Zhang JY, Wang FS, Zhang C, Fimia GM, Capobianchi MR, Piacentini M, Antinori A, Nicastri E, Maeurer M, Zumla A, Ippolito G. Expansion of myeloid-derived suppressor cells in patients with severe coronavirus disease (COVID-19). Cell Death Differ. 2020 Nov;27(11):3196-3207. doi: 10.1038/s41418-020-0572-6. Epub 2020 Jun 8. PMID: 32514047; PMCID: PMC7278239.

Zumla A, Wang FS, Ippolito G, Petrosillo N, Agrati C, Azhar EI, Chang C, El- Kafrawy SA, Osman M, Zitvogel L, Galle PR, Locatelli F, Gorman E, Cordon-Cardo C, O’Kane C, McAuley D, Maeurer M. Reducing mortality and morbidity in patients with severe COVID-19 disease by advancing ongoing trials of Mesenchymal Stromal (stem) Cell (MSC) therapy – Achieving global consensus and visibility for cellular host-directed therapies. Int J Infect Dis. 2020 Jul;96:431-439. doi: 10.1016/j.ijid.2020.05.040. Epub 2020 May 17. PMID: 32425638; PMCID: PMC7231497.

Bordoni V, Sacchi A, Cimini E, Notari S, Grassi G, Tartaglia E, Casetti R, Giancola ML, Bevilacqua N, Maeurer M, Zumla A, Locatelli F, De Benedetti F, Palmieri F, Marchioni L, Capobianchi MR, D’Offizi G, Petrosillo N, Antinori A, Nicastri E, Ippolito G, Agrati C. An Inflammatory Profile Correlates With Decreased Frequency of Cytotoxic Cells in Coronavirus Disease 2019. Clin Infect Dis. 2020 Nov 19;71(16):2272-2275. doi: 10.1093/cid/ciaa577. PMID: 32407466; PMCID: PMC7239202.

Ippolito G, Hui DS, Ntoumi F, Maeurer M, Zumla A. Toning down the 2019-nCoV media hype-and restoring hope. Lancet Respir Med. 2020 Mar;8(3):230-231. doi: 10.1016/S2213-2600(20)30070-9. Epub 2020 Feb 12. PMID: 32146924; PMCID: PMC7129403.

Tiberi S, Migliori GB, Muhwa Chakaya J, Kaesava T, Al Abri SS, Wejse C, Goletti D, Kapata N, Sotgiu G, Bomanji J, Zellweger JP, Hasan R, Irfan M, Ahmed I, Pshenichnaya N, Vasilieva I, Yeboah-Manu D, Alffenaar JW, Kim HY, Centis R, Cirillo DM, Alagna R, D’Ambrosio L, Cui X, Cao B, Maeurer M, Harries AD, Ippolito G, Raviglione M, Zumla A, Petersen E. Commemorating World TB Day 2020: “IT’S TIME” – It’s time to End the Global TB Epidemic. Int J Infect Dis. 2020 Mar;92S:S1-S4. doi: 10.1016/j.ijid.2020.03.001. Epub 2020 Mar 4. PMID: 32145464.

Zumla A, Ippolito G, Ntoumi F, Seyfert-Margolies V, Nagu TJ, Cirillo D, Chakaya JM, Marais B, Maeurer M. Host-directed therapies and holistic care for tuberculosis. Lancet Respir Med. 2020 Apr;8(4):337-340. doi: 10.1016/S2213-2600(20)30078-3. Epub 2020 Feb 27. PMID: 32113574.

Lérias JR, Paraschoudi G, de Sousa E, Martins J, Condeço C, Figueiredo N, Carvalho C, Dodoo E, Castillo-Martin M, Beltrán A, Ligeiro D, Rao M, Zumla A, Maeurer M. Microbes as Master Immunomodulators: Immunopathology, Cancer and Personalized Immunotherapies. Front Cell Dev Biol. 2020 Jan 23;7:362. doi: 10.3389/fcell.2019.00362. PMID: 32039196; PMCID: PMC6989410.

Zumla A, Hui DS, Azhar EI, Memish ZA, Maeurer M. Reducing mortality from 2019-nCoV: host-directed therapies should be an option. Lancet. 2020 Feb 22;395(10224):e35-e36. doi: 10.1016/S0140-6736(20)30305-6. Epub 2020 Feb 5. PMID: 32035018; PMCID: PMC7133595.

Lérias JR, de Sousa E, Paraschoudi G, Martins J, Condeço C, Figueiredo N, Carvalho C, Dodoo E, Maia A, Castillo-Martin M, Beltrán A, Ligeiro D, Rao M, Zumla A, Maeurer M. Trained Immunity for Personalized Cancer Immunotherapy: Current Knowledge and Future Opportunities. Front Microbiol. 2020 Jan 10;10:2924. doi: 10.3389/fmicb.2019.02924. PMID: 31998254; PMCID: PMC6967396.

Akkerman OW, Ter Beek L, Centis R, Maeurer M, Visca D, Muñoz-Torrico M, Tiberi S, Migliori GB. Rehabilitation, optimized nutritional care, and boosting host internal milieu to improve long-term treatment outcomes in tuberculosis patients. Int J Infect Dis. 2020 Mar;92S:S10-S14. doi: 10.1016/j.ijid.2020.01.029. Epub 2020 Jan 23. PMID: 31982628.

Khader SA, Divangahi M, Hanekom W, Hill PC, Maeurer M, Makar KW, Mayer- Barber KD, Mhlanga MM, Nemes E, Schlesinger LS, van Crevel R, Vankayalapati R(, Xavier RJ, Netea MG; Bill and Melinda Gates Foundation Collaboration for TB Vaccine Discovery Innate Immunity Working Group18. Targeting innate immunity for tuberculosis vaccination. J Clin Invest. 2019 Sep 3;129(9):3482-3491. doi: 10.1172/JCI128877. PMID: 31478909; PMCID: PMC6715374.

Rao M, Dodoo E, Zumla A, Maeurer M. Immunometabolism and Pulmonary Infections: Implications for Protective Immune Responses and Host-Directed Therapies. Front Microbiol. 2019 May 7;10:962. doi: 10.3389/fmicb.2019.00962. PMID: 31134013; PMCID: PMC6514247.

Lérias JR, Paraschoudi G, Silva I, Martins J, de Sousa E, Condeço C, Figueiredo N, Carvalho C, Dodoo E, Jäger E, Rao M, Maeurer M. Clinically Relevant Immune Responses against Cytomegalovirus: Implications for Precision Medicine. Int J Mol Sci. 2019 Apr 23;20(8):1986. doi: 10.3390/ijms20081986. PMID: 31018546; PMCID: PMC6514820.

Rao M, Ligeiro D, Maeurer M. Precision medicine in the clinical management of respiratory tract infections including multidrug-resistant tuberculosis: learning from innovations in immuno-oncology. Curr Opin Pulm Med. 2019 May;25(3):233-241. doi: 10.1097/MCP.0000000000000575. PMID: 30883448.

Abubakar I, Chakaya J, Maeurer M, Zumla A. Towards optimal treatment for latent Mycobacterium tuberculosis infection. Lancet Respir Med. 2019 Mar;7(3):195-197. doi: 10.1016/S2213-2600(19)30036-0. PMID: 30823969.

Rao M, Ippolito G, Mfinanga S, Ntoumi F, Yeboah-Manu D, Vilaplana C, Zumla A, Maeurer M. Latent TB Infection (LTBI) – Mycobacterium tuberculosis pathogenesis and the dynamics of the granuloma battleground. Int J Infect Dis. 2019 Mar;80S:S58-S61. doi: 10.1016/j.ijid.2019.02.035. Epub 2019 Feb 26. PMID: 30822547.

Petersen E, Rao M, Ippolito G, Gualano G, Chakaya J, Ntoumi F, Moore D, Allen R, Gaskell K, Öhd JN, Hergens MP, Krishnamoorthy S, Ugarte-Gil C, Kirwan DE, Honeyborne I, McHugh TD, Köser CU, Kranzer K, Tiberi S, Migliori GB, Mao Q, Yang Y, Oliveira SP, Cardoso RF, Detjen A, Marais B, de Gijsel D, von Reyn CF, Goscé L, Abubakar I, Maeurer M, Zumla A. World Tuberculosis Day March 24th 2019 Theme: “It’s TIME” – International Journal of Infectious Diseases Tuberculosis Theme Series. Int J Infect Dis. 2019 Mar;80S:S1-S5. doi: 10.1016/j.ijid.2019.02.024. Epub 2019 Feb 23. PMID: 30802624.

Sinclair G, Benmakhlouf H, Martin H, Maeurer M, Dodoo E. Adaptive hypofractionated gamma knife radiosurgery in the acute management of brainstem metastases. Surg Neurol Int. 2019 Jan 29;10:14. doi: 10.4103/sni.sni_53_18. PMID: 30783544; PMCID: PMC6367951.

Rao M, Ippolito G, Mfinanga S, Ntoumi F, Yeboah-Manu D, Vilaplana C, Zumla A, Maeurer M. Improving treatment outcomes for MDR-TB – Novel host-directed therapies and personalised medicine of the future. Int J Infect Dis. 2019 Mar;80S:S62-S67. doi: 10.1016/j.ijid.2019.01.039. Epub 2019 Jan 24. PMID: 30685590.

Smith JR, Pe’er J, Belfort RN, Cardoso F, Carvajal RD, Carvalho C, Coupland SE, Desjardins L, Francis JH, Gallie BL, Gombos DS, Grossniklaus HE, Heegaard S, Jager MJ, Kaliki S, Ksander BR, Maeurer M, Moreno E, Pulido JS, Ryll B, Singh AD, Zhao J, Parreira A, Wilson DJ, O’Brien JM. Proceedings of the Association for Research in Vision and Ophthalmology and Champalimaud Foundation Ocular Oncogenesis and Oncology Conference. Transl Vis Sci Technol. 2018 Jan 9;8(1):9. doi: 10.1167/tvst.8.1.9. PMID: 30652059; PMCID: PMC6333107.

Sinclair G, Benmakhlouf H, Martin H, Brigui M, Maeurer M, Dodoo E. The role of radiosurgery in the acute management of fourth ventricle compression due to brain metastases. Surg Neurol Int. 2018 May 29;9:112. doi: 10.4103/sni.sni_387_17. PMID: 29930878; PMCID: PMC5991270.

Valentini D, Rao M, Meng Q, von Landenberg A, Bartek J Jr, Sinclair G, Paraschoudi G, Jäger E, Harvey-Peredo I, Dodoo E, Maeurer M. Correction: Identification of neoepitopes recognized by tumor-infiltrating lymphocytes (TILs) from patients with glioma. Oncotarget. 2018 Dec 4;9(95):36817. doi: 10.18632/oncotarget.26447. Erratum for: Oncotarget. 2018 Apr 13;9(28):19469-19480. PMID: 30613370; PMCID: PMC6298404.

Sinclair G, Benmakhlouf H, Brigui M, Maeurer M, Dodoo E. The concept of rapid rescue radiosurgery in the acute management of critically located brain metastases: A retrospective short-term outcome analysis. Surg Neurol Int. 2018 Oct 30;9:218. doi: 10.4103/sni.sni_480_17. PMID: 30505620; PMCID: PMC6219289.

Meng Q, Valentini D, Rao M, Dodoo E, Maeurer M. CMV and EBV targets recognized by tumor-infiltrating B lymphocytes in pancreatic cancer and brain tumors. Sci Rep. 2018 Nov 20;8(1):17079. doi: 10.1038/s41598-018-34710-2. PMID: 30459443; PMCID: PMC6244284.

Meng Q, Valentini D, Rao M, Moro CF, Paraschoudi G, Jäger E, Dodoo E, Rangelova E, Del Chiaro M, Maeurer M. Neoepitope targets of tumour-infiltrating lymphocytes from patients with pancreatic cancer. Br J Cancer. 2019 Jan;120(1):97-108. doi: 10.1038/s41416-018-0262-z. Epub 2018 Oct 31. PMID: 30377343; PMCID: PMC6325142.

Meng Q, Valentini D, Rao M, Maeurer M. KRAS RENAISSANCE in Tumor Infiltrating B Cells in Pancreatic Cancer. Front Oncol. 2018 Sep 19;8:384. doi: 10.3389/fonc.2018.00384. PMID: 30283732; PMCID: PMC6156365.

Luo XH, Meng Q, Rao M, Liu Z, Paraschoudi G, Dodoo E, Maeurer M. The impact of inflationary cytomegalovirus-specific memory T cells on anti-tumour immune responses in patients with cancer. Immunology. 2018 Nov;155(3):294-308. doi: 10.1111/imm.12991. Epub 2018 Sep 10. PMID: 30098205; PMCID: PMC6187203.

Zhenjiang L, Rao M, Luo X, Valentini D, von Landenberg A, Meng Q, Sinclair G, Hoffmann N, Karbach J, Altmannsberger HM, Jäger E, Peredo IH, Dodoo E, Maeurer M. Cytokine Networks and Survivin Peptide-Specific Cellular Immune Responses Predict Improved Survival in Patients With Glioblastoma Multiforme. EBioMedicine. 2018 Jul;33:49-56. doi: 10.1016/j.ebiom.2018.06.014. Epub 2018 Jun 29. PMID: 30049387; PMCID: PMC6085502.

Liu Z, Poiret T, Meng Q, Rao M, von Landenberg A, Schoutrop E, Valentini D, Dodoo E, Peredo-Harvey I, Maeurer M. Epstein-Barr virus- and cytomegalovirus- specific immune response in patients with brain cancer. J Transl Med. 2018 Jul 3;16(1):182. doi: 10.1186/s12967-018-1557-9. PMID: 29970101; PMCID: PMC6029420.

Meng Q, Valentini D, Rao M, Liu Z, Xie S, Morgell A, Dodoo E, Löhr M, Rangelova E, Del Chiaro M, Ernberg I, Maeurer M. Prediction of improved survival in patients with pancreatic cancer via IL-21 enhanced detection of mesothelin epitope-reactive T-cell responses. Oncotarget. 2018 Apr 27;9(32):22451-22459. doi: 10.18632/oncotarget.25121. PMID: 29854291; PMCID: PMC5976477.

Valentini D, Rao M, Meng Q, von Landenberg A, Bartek J Jr, Sinclair G, Paraschoudi G, Jäger E, Harvey-Peredo I, Dodoo E, Maeurer M. Identification of neoepitopes recognized by tumor-infiltrating lymphocytes (TILs) from patients with glioma. Oncotarget. 2018 Apr 13;9(28):19469-19480. doi: 10.18632/oncotarget.24955. Erratum in: Oncotarget. 2018 Dec 4;9(95):36817. PMID: 29731959; PMCID: PMC5929402.

Poiret T, Axelsson-Robertson R, Remberger M, Luo XH, Rao M, Nagchowdhury A, Von Landenberg A, Ernberg I, Ringden O, Maeurer M. Cytomegalovirus-Specific CD8+ T-Cells With Different T-Cell Receptor Affinities Segregate T-Cell Phenotypes and Correlate With Chronic Graft-Versus-Host Disease in Patients Post- Hematopoietic Stem Cell Transplantation. Front Immunol. 2018 Apr 10;9:760. doi: 10.3389/fimmu.2018.00760. PMID: 29692783; PMCID: PMC5903031.

Nagu TJ, Aboud S, Matee MI, Maeurer MJ, Fawzi WW, Mugusi F. Effects of isoniazid resistance on TB treatment outcomes under programmatic conditions in a high-TB and -HIV setting: a prospective multicentre study-authors’ response. J Antimicrob Chemother. 2018 Jun 1;73(6):1735. doi: 10.1093/jac/dky104. PMID: 29635525.

Maeurer M, Rao M, Zumla A. B cells or T cells in TB: a continuing conundrum. Lancet Respir Med. 2018 Apr;6(4):237-238. doi: 10.1016/S2213-2600(18)30080-8. PMID: 29595500.

Tiberi S, du Plessis N, Walzl G, Vjecha MJ, Rao M, Ntoumi F, Mfinanga S, Kapata N, Mwaba P, McHugh TD, Ippolito G, Migliori GB, Maeurer MJ, Zumla A. Tuberculosis: progress and advances in development of new drugs, treatment regimens, and host-directed therapies. Lancet Infect Dis. 2018 Jul;18(7):e183-e198. doi: 10.1016/S1473-3099(18)30110-5. Epub 2018 Mar 23. Erratum in: Lancet Infect Dis. 2018 Apr 27;: PMID: 29580819.

Tiberi S, Petersen E, Maeurer M, Ntoumi F, Yeboa-Manu D, Mwaba P, Vilaplana C, Dar O, Bates M, Corrah T, Rao M, Kapata N, Azhar EI, Memish ZA, Mfinanga S, Aseffa A, Ippolito G, Migliori GB, Zumla A. Taking forward the Stop TB Partnership and World Health Organization Joint Theme for World TB Day March 24th 2018 – “Wanted: Leaders for a TB-Free World. You can make history. End TB”. Int J Infect Dis. 2018 Mar;68:122-124. doi: 10.1016/j.ijid.2018.03.002. Epub 2018 Mar 22. PMID: 29571578.

Rao M, Valentini D, Zumla A, Maeurer M. Evaluation of the efficacy of valproic acid and suberoylanilide hydroxamic acid (vorinostat) in enhancing the effects of first-line tuberculosis drugs against intracellular Mycobacterium tuberculosis. Int J Infect Dis. 2018 Apr;69:78-84. doi: 10.1016/j.ijid.2018.02.021. Epub 2018 Mar 2. PMID: 29501835.

Liu Z, Poiret T, Persson O, Meng Q, Rane L, Bartek J Jr, Karbach J, Altmannsberger HM, Illies C, Luo X, Harvey-Peredo I, Jäger E, Dodoo E, Maeurer M. NY-ESO-1- and survivin-specific T-cell responses in the peripheral blood from patients with glioma. Cancer Immunol Immunother. 2018 Feb;67(2):237-246. doi: 10.1007/s00262-017-2066-z. Epub 2017 Oct 20. PMID: 29058035; PMCID: PMC5799356.

Loading
Por favor aguarde...