Marco Colonna

 Host

Carlos Minutti, PhD, Immunoregulation Lab

Venue

Seminar Room

Abstract

His laboratory studies innate immune recognition and immunoreceptor signalling. Over three decades his work has made foundational contributions to the field, including the identification of plasmacytoid dendritic cells as the principal source of type I interferons in antiviral immunity, the discovery of the TREM and LILR receptor families, and the characterisation of innate lymphoid cells in mucosal immunity. His current research spans neuroimmunology and neurodegeneration, mucosal immunology and cancer immunology, with recent work defining the role of TREM2 in neurodegeneration and cancer, and the development and function of RORγt⁺ dendritic cells in mucosal tolerance.

Bio

Marco Colonna is Full Professor and Investigator at the Center for Computational and Integrative Biology, Massachusetts General Hospital and Harvard Medical School, and an Institute Member at the Broad Institute, which he joined in 2026 following 25 years at Washington University School of Medicine in St. Louis. He trained in internal medicine at the University of Parma, completed his postdoctoral training at Harvard Medical School, and was a scientific member of the Basel Institute for Immunology.

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About the CR Colloquia Series

Champalimaud Research (CR) Colloquia Series is a seminar programme organised by the Champalimaud Centre for the Unknown to promote the discussion about the most interesting and significant questions in neuroscience and physiology & cancer with appointed speakers by the CR Community.