Single-Neuron Mechanisms of Temporal Structure Coding in the Human Brain

Host

John Krakauer, MD, Cognitive-Motor Interface Lab

Venue

Seminar Room

Abstract

Extracting patterns of events is fundamental to learning, memory, and planning, yet the neural mechanisms supporting this ability remain elusive. In this talk, I will present evidence that neurons in the human hippocampus and entorhinal cortex integrate information about what happens and when it happens to form durable, predictive representations of the temporal structure of experience. In addition to reviewing these core findings, I will briefly discuss the methodology of human single-neuron recordings and outline ongoing and future work aimed at developing unified theoretical frameworks that connect temporal coding with spatial and conceptual representations in human hippocampal–entorhinal circuits.

Bio

Dr. Pawel Tacikowski is an Assistant Professor in Cognitive Computational Neuroscience at the University of Coimbra. He previously held postdoctoral positions at the Karolinska Institutet and UCLA. His research combines experimental psychology, neuroimaging, mixed-reality environments, and human single-neuron recordings to uncover the neural mechanisms that shape how we perceive the world and understand ourselves.

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About CR Colloquia Series

Champalimaud Research (CR) Colloquia Series is a seminar programme organised by the Champalimaud Centre for the Unknown to promote the discussion about the most interesting and significant questions in neuroscience and physiology & cancer with appointed speakers by the CR Community.