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About

Orger Lab

Orger Lab

Our goal is to understand how the brain integrates sensory information, selects, and executes appropriate actions. In particular, we aim to determine the organization and function of neural circuits underlying visually guided behaviors. We use the zebrafish as a model organism because it allows us to visualize and manipulate activity in neural circuits throughout a vertebrate brain. As early as one week post-fertilization, zebrafish display a rich repertoire of innate visual behaviors, following moving patterns, avoiding predators, and tracking and capturing live prey. With no skull and transparent skin, the entire volume of the brain can be imaged non-invasively in one field of view, and many neurons are individually identifiable from fish to fish. Our approach has three main themes: 1) Quantitative analysis of behavior. 2) Whole brain imaging of neural activity dynamics in the behaving animal. 3) Perturbation of identified neurons to reveal their role in sensorimotor integration. In parallel, we are developing new genetic tools that allow more specific targeting and manipulation of identified cell types.

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Get in touch

To find out more about our lab, contact Michael Orger via email.

Team

Orger Lab

Know our Team

Michael Orger

Principal Investigator

Aaron Ostrovsky

Senior Technician

Adrien Jouary

Postdoctoral Researcher

Alexandre Laborde

Research Technician

Claudia Feierstein

Research Associate

Donovan Cassidy-Nolan

Elena Hindinger

2017 INDP PhD Student

Gokul Rajan

Postdoctoral Researcher

Jens Bierfeld

2011 INDP PhD Student

Joaquim Contradanças

2017 INDP PhD Student

Lucas Martins

2017 INDP PhD Student

Pedro Tomás

2021 INPDP PHD Student

Ruth Diez del Corral

Research Associate

Sabine Renninger

Postdoctoral Researcher

Thomas Mullen

External PhD Student

Publications

Orger Lab

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