12 March 2025

The secret DNA circles fueling Pancreatic Cancer’s aggression

A New Player in Pancreatic Cancer

The team found that some pancreatic cancer cells gain a major survival edge by carrying copies of critical cancer genes—such as MYC—on circular pieces of DNA that exist outside chromosomes, the structures that house most of our genetic material. Known as ecDNA, these genetic rings float freely in the cell nucleus, enabling tumour cells to swiftly ramp up gene expression, change their shape, and survive in otherwise hostile environments.

Under Pressure: How Mechanical Forces Influence Structural Plasticity

Host

Rita Cardoso-Figueiredo, Behavior and Metabolism Lab


Venue

Seminar room

Spatial Omics and AI: Bridging Discovery and Translational Medicine

The "Spatial Omics and AI: Bridging Discovery and Translational Medicine" symposium, is a free event which will explore the impact of Spatial Proteomics and AI in Translational Research and Life Sciences.

Keynote speakers include: 

- Prof. Emma Lundberg (Stanford University)
- Dr. Andrea J. Radtke (Leica Microsystems)
- Dr. Thierry Nordmann (Max Planck Institute)
- Dr. Giuseppe Diaferia (Champalimaud Foundation)

Diana Cadete

Niche Remodeling and Iron Metabolism in Acute Myeloid Leukemia

Host

Cristina João, PhD, Myeloma Lymphoma Research Group


Venue

Seminar room

27 February 2025

Champalimaud Foundation Investigator Receives EASO - Novo Nordisk Foundation New Investigator Award

Each year, the European Association for the Study of Obesity (EASO) and the Novo Nordisk Foundation, honours exceptional research contributions that enhance our understanding of obesity, its causes, complications, prevention, and management. 

Neurobiology of Kinship Behavior

Host

Inês Dias & Ana Rita Mendes, PhD, Neuroethology Lab


Venue

Seminar room

Type 2 Cytokines: A Story of Macrophages, Matrix & Metazoan Parasites

Host

Carlos Minutti, PhD, Immunoregulation Lab


Venue

Seminar room

Unveiling Solid Tumor Microenvironment for Revolutionary Nano-Immunotherapies

Host

Cristina João, Myeloma Lymphoma Research Group


Venue

Seminar room

Development and Evolution of Neuronal Diversity in the Insect Visual System

Host

Christa Rhiner, Stem Cells and Regeneration Lab


Venue

Seminar room

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