[THIS CALL IS NOW CLOSED]

Since the 1990s, non-invasive brain stimulation has grown from an experimental idea into an established tool for treating depression as well as advancing neuroscience research. Among these technologies, repetitive transcranial magnetic stimulation (rTMS) is clinically validated and used to treat major depressive disorder, also known as unipolar depression.

Thinking about the past and how it shaped the present is never simple. But Zach Mainen, who has been here since day one, was a natural person to revisit the “Then and Now” of the Champalimaud Foundation (CF). We spoke about what it meant to take on a new and unpredictable project, and how the dream of a small group gradually became reality. I hope this story inspires you to step into the unknown and to trust that even when the future feels uncertain, it can still unfold into something remarkable.