At the Champalimaud Colorectal Cancer Conference, last February, Gina Brown, from the Imperial College London, questioned the validity of the current staging strategy for colon cancer. Indeed, research shows that lymph nodes are not the main culprit in colon cancer spread, and can actually be a sign that the patient’s immune system is fighting back. 

Coordinated by Professor Ana Santos Almeida, principal investigator of a translational laboratory at the GIMM Foundation - Gulbenkian Institute for Molecular Medicine (GIMM-CARE), this study will take place at the Champalimaud Foundation, in collaboration with Dr. José Azevedo, surgeon of the Colorectal Cancer Group of the Digestive Unit of the Champalimaud Clinical Center, and at the Hospital de Santa Maria, with the participation of oncologists Professor Luís Costa and Dr. André Mansinho.

Host

Albino Oliveira-Maia, MD, PhD, Neuropsychiatry Unit

Venue

Seminar room

Host

Margarida Caio, Stem Cells and Regeneration Lab

Venue

Seminar room

A Call for one Research Fellow for a Master student is open at Fundação D. Anna de Sommer Champalimaud e Dr. Carlos Montez Champalimaud (Champalimaud Foundation) in the context of the project entitled “Viscerosensory patwhays in nutrient postingestive signalling”, with reference “PTDC/SAU-NUT/3507/2021” from the call Nº PTDC2021, funded by the Fundação para a Ciência e a Tecnologia (FCT), through Portuguese National Funds (PIDDAC).

A New Player in Pancreatic Cancer

The team found that some pancreatic cancer cells gain a major survival edge by carrying copies of critical cancer genes—such as MYC—on circular pieces of DNA that exist outside chromosomes, the structures that house most of our genetic material. Known as ecDNA, these genetic rings float freely in the cell nucleus, enabling tumour cells to swiftly ramp up gene expression, change their shape, and survive in otherwise hostile environments.

Host

Rita Cardoso-Figueiredo, Behavior and Metabolism Lab

Venue

Seminar room

The "Spatial Omics and AI: Bridging Discovery and Translational Medicine" symposium, is a free event which will explore the impact of Spatial Proteomics and AI in Translational Research and Life Sciences.

Keynote speakers include: 

- Prof. Emma Lundberg (Stanford University)
- Dr. Andrea J. Radtke (Leica Microsystems)
- Dr. Thierry Nordmann (Max Planck Institute)
- Dr. Giuseppe Diaferia (Champalimaud Foundation)

Developed by an international consortium of 117 experts in legal, ethical, clinical, and AI domains—and featuring Champalimaud Foundation (CF) Principal Investigator Nikolas Papanikolaou—the framework provides a detailed roadmap for creating trustworthy medical AI, from the earliest design stages all the way through clinical deployment and monitoring.