• Clinical Services
Clinical Services
Nuclear Medicine Service
Fundação Champalimaud

Nuclear Medicine

Much more than a means of diagnosis

Generically, nuclear medicine is an independent medical specialty used for both diagnosis and treatment. It is a diagnostic tool for detecting disease, determining the disease stage and evaluating therapeutic responses for different types of cancer, based on the use of radiopharmaceuticals to obtain functional images. It also has very important therapeutic use, particularly for, among others, endocrine and neuroendocrine pathologies, bone metastases in patients with prostate cancer, and thyroid cancer metastases.

Nuclear Medicine

Diagnostics and Therapeutics

A double function

The fundamental basis of nuclear medicine is the radiopharmaceutical – an active substance containing a radionuclide that emits radiation. The radiopharmaceutical administered (orally or intravenously) to the patient is taken up and retained by cells and tissues. The capacity to localise specific organs and receptor cells allows the radiopharmaceutical to supply information about the disease process, based on function and cellular anatomy. The radiopharmaceutical emissions are picked up by external detectors, such as the gamma camera (scintigraphy equipment, SPECT) or PET/CT tomography, which create images from this radiation. At the Champalimaud Clinical Centre, our principle is to use radiopharmaceuticals to provide the best possible service and rapid responses in all areas of nuclear medicine, both diagnostic and therapeutic. This includes generic nuclear medicine, single-photon emission computed tomography, positron emission tomography (PET/CT), bone densitometry, nuclear haematology, and radionuclide therapeutics.

Nuclear Medicine

The activities developed and the use of radiopharmaceuticals are intended to help diagnose and define the most adequate clinical orientation for optimal treatment, but they also have therapeutic capabilities beyond oncology. But it is in oncology that they play a major therapeutic role.

Professor Dr. Durval Costa, Head of the Nuclear Medicine Service

Nuclear Medicine

Radiopharmaceuticals

Nuclear Medicine - Radiopharmaceuticals

Using radiation for treatment

The main advantage of using radiopharmaceuticals for the treatment of pathologies is that alpha and beta emission radionuclides can kill cells very quickly. This efficiency, combined with the fact that their radiation is very short-range, makes radiopharmaceuticals an effective and safe therapeutic option. In most situations, it is administered in an outpatient regime, but whenever necessary, patients can be hospitalised in an adequately prepared room, where they can rest until the radiation is cleared from their system, being released only when it is safe to do so. The Nuclear Medicine Service of the Champalimaud Clinical Centre has the capacity and availability to produce its own radiopharmaceuticals, a process that is still not routine in many Nuclear Medicine services in Portugal or even internationally. The Service has been responsible for the introduction of new diagnostic and therapeutic methods using radiopharmaceuticals. Radioactive pharmaceuticals were not used until recently in this context – and for some of them, the CCC was a pioneer in Portugal. Iodine-1177, Lu-DOTATATE23, technetium-99m, iodine-131, and 177 Lu-DOTATATE are examples of this.

Nuclear Medicine

Clinical Research

Pioneering the use of new radiopharmaceuticals

Our whole experienced team is actively involved in clinical research and in many other externally funded research projects whose goal is to improve diagnostic quality and nuclear medicine therapeutics. Among the scientific activities of the service are:

1. Dopaminergic neurotransmission in feeding learning and obesity;

2. Distress and regional brain metabolism: a correlational study in metastatic breast cancer patients;

3. Automatic detection of metastases by Bone Scintigraphy BTSCAD – Bone Tumour Scan – CAD;

4. Labelling anti-PD-L1-mAb with radionuclide for imaging PD-L1 expression in cancer - Material Transfer Agreement (MTA), Genentech-Roche.

Nuclear Medicine - Clinical Research

Nuclear Medicine

Certification

Nuclear Medicine - Certification

A certified service

The Nuclear Medicine Service of the Champalimaud Clinical Centre has been recognised through accreditation as a Nuclear Medicine Service (European Union of Medical Specialists - Section and Board of Nuclear Medicine) for the period 2019-2023.

Nuclear Medicine

The Team

Meet our team

The Nuclear Medicine Service is comprises a dedicated and specialised team of professionals: an administrative team for scheduling exams, specialised physicians for clinically justifying the use of ionizing radiation, technicians for performing the exams, operational assistants who help to ensure the patients’ well-being, specialised physicists for quality control and radiological protection, and pharmacists with radiopharmacy skills as supervisors.

Durval Costa

Durval Costa, Director, MD, PhD

Nuclear Medicine

Ana Canudo

Ana Canudo

Nuclear Medicine Technician

Ana Capacho

Ana Capacho

Pharmacy

Andrea Gomes

Operational Assistant

Ângelo Silva

Ângelo Silva, MD

Nuclear Medicine

Bárbara Freitas

Nuclear Medicine Technician

Bárbara Marques

Operational Assistant

Cátia Rodrigues

Administrative Assistant

Diana Dantas

Diana Dantas

Nuclear Medicine Technician

Francisco Oliveira

Francisco Oliveira, PhD

Researcher

Joana Castanheira

Joana Castanheira, MD

Nuclear Medicine

Mariana Silva

Mariana Silva

Nuclear Medicine Technician

Marisa Machado

Marisa Machado

Nuclear Medicine Technician

Miguel Andrade

Miguel Andrade

Nuclear Medicine Technician

Patrícia Pereira

Patrícia Pereira

Operational Assistant

Paulo Ferreira

Paulo Ferreira

Physicist

Rita Oliveira

Rita Oliveira

Nuclear Medicine Technician

Rui Parafita

Physicist

Sandra Chaves

Nuclear Medicine Technician

Sofia Vaz

Sofia Vaz, MD

Nuclear Medicine

Sónia Teixeira

Nuclear Medicine Technician

Teresa Cardoso

Teresa Cardoso

Administrative Assistant

Vanessa Machado

Vanessa Machado

Administrative Assistant

Loading
Please wait...