• Research Groups
Research Groups
Cancer and Stem Cell Biology


Sánchez Danés Lab

Sánchez Danés Lab

Most tumours are heterogeneous at the cellular and (epi)genetic levels. This heterogeneity has been proposed to be responsible for tumour progression, metastasis and resistance to therapy. Our goal is to understand the contribution of the different tumour cell populations and genetic alterations to cancer progression and response to therapy. We do that by combining genetic lineage tracing, clonal analysis, imaging techniques, tumour organoid cultures and functional experiments in vivo and in vitro. We use the most frequent human cancer – basal cell carcinoma – and one of the most common pediatric cancers – medulloblastoma – as the models for our studies. Both types of cancer arise upon the constitutive activation of the Hedgehog signalling pathway.



If you are interested in joining our group, please contact Adriana Sánchez Danés via email.


Sánchez Danés Lab


Sánchez Danés Lab

Know our Team

Adriana Sánchez Danés

Principal Investigator, ERA Chair

Ana Sofia Marques


Erik Cardoso

Masters Student

Laura Ward

Project Manager

Patrícia Borges

Senior Technician

Raquel Soares


Ana Raquel Tomás

Raquel Tomás, PhD

Postdoctoral Researcher

Sara Canato

Postdoctoral Researcher

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