A portion of human gut – just removed from the abdomen of a colon cancer patient and opened in half so as to give access to its inner mucosa, – sits on the countertop. A technician starts to scan it with the tip of an optical fibre, hovering over the surface of the sample without touching it. On the scanned zones, streaks of various colours, as if the tissue is being “painted” by the laser beam coming out of the fibre optic. 

The BALANCE project, from the Cancer and Stem Cell Biology Lab at Champalimaud Research, will focus on medulloblastoma, one of the most common malignant brain tumours in children, and aims to “discover to what extent the developing brain is plastic and capable of compensating for the disturbances caused by the formation of a tumour, while maintaining its normal development and function”, as those responsible for the study say.

Researchers from the Behavioral Neuroscience Laboratory at the Champalimaud Foundation, in Portugal, strive to understand how social context influences the individual's response to threats. 

Previously, they have shown that when fruit flies in a group are faced with an inescapable threat, they lower their defences compared to when alone. They further observed that if the other flies freeze, then so will the individual; when the group starts moving again, the individual quickly follows. Being in tune with the surrounding flies seems to bring security.

A study performed by the team of haematologist Cristina João, who leads the Myeloma and Lymphoma Research Group at the Champalimaud Centre for the Unknown, suggests that it may be possible, in a near future, to diagnose and monitor the progression of multiple myeloma (MM) by simply using a blood sample. Their results were published today (21/06/2022) in the journal Frontiers in Oncology.