09 February 2021

Obesity: sensitivity to sweet taste predicts the amount of weight loss that will be induced by stomach surgery to treat obesity

A study led by scientists from the Champalimaud Centre for the Unknown, in Lisbon, concludes that bariatric surgery – that is, procedures used to treat severe obesity by reconfiguring the gastrointestinal tract –, leads to greater weight loss in patients who, before the surgery, had a heightened perception of sweetness.

05 February 2021

Imaging of a living brain can help clearly differentiate between two types of dementia

American actor Robin Williams had a neurodegenerative brain disease called dementia with Lewy bodies (DLB): a distressing disease, with symptoms in common with Alzheimer’s disease (AD) and Parkinson’s disease (PD). But unlike these two conditions, DLB also entails prominent mood and cognitive swings, sleep disorders, and vivid, sometimes terrifying, visual hallucinations.

04 January 2021

Why do males have to wait for “round 2”? The reason may be different from what we think.

If you type into a search engine - “why do men have to wait before having sex again?” - you will very quickly come across Prolactin. This little hormone is thought to be involved in hundreds of physiological processes in the body. Among them is the male post-ejaculatory refractory period. This period begins when a male ejaculates and ends when he recovers his sexual capacity. 

22 December 2020

Noam Shemesh Receives Prize from Santa Casa da Misericórdia de Lisboa

Since 2013, the charitable organisation Santa Casa da Misericórdia de Lisboa annually selects three research projects, led by scientists in Portugal. This year, the project of Noam Shemesh, a principal investigator at Champalimaud Foundation, was selected for one of the awards, called the Mantero Belard Prize.

20 October 2020

Rethinking the link between cannabinoids and learning

Cannabinoids have a strong influence on how our brains work and how we behave. Many people are only aware of the recreational aspect of cannabinoids. But in fact these molecules naturally exist in our brains where they participate in various intrinsic processes.

Altered cannabinoid signalling, for instance due to chronic use of marijuana, results in a range of impairments. Similarly, mice lacking cannabinoid receptors exhibit reduced activity levels, as well as deficits in learning and memory. 

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