29 March 2018

Life of PI: From medicine to neuroscience and back

Albino Oliveira-Maia has always navigated between medical practice and scientific research. In his opinion, these two worlds, which are still not talking to each other in a fluid manner, need others like him to bring them closer.

All things considered, my role may be to find links between medicine and science, to develop a model of proximity between these two domains.Albino Oliveira-Maia

05 April 2018

Carmen Sandi: “There is a causal link between mitochondrial function and rank in social hierarchy”

Can brain biology negatively affect an individual’s position in society? The answer seems to be yes – and Carmen Sandi’s work has shown that the mitochondria (the cell’s batteries) are an important player. Could this negative impact be reduced with drugs?

When we pharmacologically inhibited the activity of the mitochondria, the animals lost in social competitions.Carmen Sandi

12 April 2018

Being a "food lover" is not enough to explain why people become obese

Many experts think that obesity is essentially the result of being hooked on food. But a new study reveals a much more complex reality.

We often hear that obesity ‘is like an addiction’. [But] food reward is not the main reason for obesity. Therefore, food addiction is not the whole story.Albino Oliveira-Maia

Read the full story here

16 April 2018

Run faster, learn better

Learning and performance can be enhanced by locomotor activity in mice, concludes a new study. The scientists sought to understand the cellular changes in the cerebellum that accompany learning.

The finding could well apply to other forms of cerebellar learning in humansCatarina Albergaria

Read the full story here

16 April 2018

CR Researchers discover hidden structure of enigmatic "backwards" neural connections

For decades the neuroscience community has been baffled by the existence of dense connections in the brain that seem to be going “backwards”. These connections, which span extensively across distant areas of the neocortex – the part of the brain responsible for higher cognitive functions – are clearly conveying important information. But until now, the organisation of the connections and therefore their possible role, was largely unknown.

03 May 2018

Humans of science: Gautam Agarwal

Who are today’s scientists? Inspired by the project “Humans of New York”, Ar Magazine turns the spotlight on individual humans of science every month.

Name: Gautam Agarwal
Lab: Systems Neuroscience | Mainen Lab
Project: A video-game-based task to study complex skill-learning in an online population

More…

14 May 2018

Researcher from the Champalimaud Centre for the Unknown elected EMBO member

Among this year’s new members, there is just one scientist working in Portugal – and he is at the Champalimaud Centre for the Unknown.

Eduardo Moreno, from the Champalimaud Centre for the Unknown (CCU), in Lisbon, is one of the 53 scientists to have been elected this year permanent members of the European Molecular Biology Organization (EMBO), this institution announced today (Monday, May 14th). He is the only new permanent member working in Portugal.

17 May 2018

Life of PI: In search of the rules that govern the social life of living cells

For years, Eduardo Moreno has been unraveling how competition for survival between cells in an organism plays out to make it develop healthily – or, as it ages, give rise to cancer and other diseases.

For me, [cell competition] was just natural selection at work inside the organism.Eduardo Moreno

Read the full story here

31 May 2018

Science Snapshot: Microbial Mind Control

Do the microbes that live inside our gut have access to areas of our body we might feel more private about, such as our brain?

Scientists at the Champalimaud Centre for the Unknown discovered that they actually do!

In this episode of Science Snapshots, Carlos Ribeiro, head of the Behaviour and Metabolism lab, talks about how his team found that gut bacteria “speak” with the brain to control a key aspect of behaviour: food choice.

27 June 2018

Serotonin speeds learning

Why do treatments with antidepressants like Prozac seem to work better when combined with behavioral therapies, which promote the learning of positive behaviors by the depressed patient? A new study suggests a possible explanation.

The study found that serotonin enhances the speed of learning. When serotonin neurons were activated artificially, using light, it made mice quicker to adapt their behavior in a situation that required such flexibility. Zach Mainen

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