The results of the most recent European Research Council (ERC)  Advanced Grants have been announced today (June 17th). In Portugal, the ERC selected two new projects in the area of ​​life sciences, which in total will receive 5M€. 

The ERC funding, worth in total €721M, will go to 281 leading researchers across Europe. In the case of life sciences, 732 proposals were submitted and 83 were selected for funding, which represents a success rate of approximately 11%. 

From philosophical zombies and the purpose of dreaming, to measuring consciousness like temperature and why brains aren’t computers, Seth unpacks the idea that our experience of reality – and of ourselves – is a kind of waking dream, a “controlled hallucination”, shaped by prediction, perception, and the body’s primal drive to stay alive.

His theory of what it means to ‘be you’ challenges how we understand perception – and turns what you thought you knew about yourself on its head.

The problem with averages

Imagine you’re deciding whether to wait in line for your favourite meal at a busy restaurant or grab a quick snack at the nearest café. Your brain weighs not just how good the meal might be, but also how long it will take to get it.

“I love talking about the molecular structure [I discovered]”, said Ardem Patapoutian, who leads a lab at the Scripps Research Institute in San Diego, as he was presenting his work to an audience gathered at the Champalimaud Foundation (CF), in Lisbon, last week. “It's very easy for me to talk about it when I have PowerPoint slides, but what if I'm in a restaurant or in a bar and I want to tell someone about how it works? I decided to get a tattoo of the structure and I want to share it with you.”

What drives someone to fear their own thoughts, or an Ethiopian schoolgirl to eat the wall of her house, bit by bit? Why do millions of us get stuck in loops of doubt and dread? And what does it mean to have a brain that simply won’t let go?

An international team, led by researchers at the Champalimaud Foundation (CF), has shown – for the first time in a realistic way – that it may be possible, in the future, to diagnose Parkinson’s disease (PD) years earlier, by scanning people’s brains with functional magnetic resonance imaging (fMRI). Although there are treatment options after diagnosis, there is no cure.  Therapies are continually improving — with ongoing research aiming to slow or even alter the course of the disease - investing in the research of methods that enable much earlier diagnosis is crucial.

When a fruit fly is navigating straight forward at high speed, why does it know that it’s not straying off course? Because as long as the fly moves directly forward, the visual scene shifts from front to back in a near-perfect mirror image across both retinas – generating, in other words, a symmetrical visual motion pattern. This pattern, known as “optic flow”, provides a powerful cue for detecting self-motion and maintaining direction.

The conference Moving Beyond, which took place at the Champalimaud Foundation on April 3 and 4, 2025, was organised to gather world scientific leaders in the field of “exercise oncology”.

During the two-day conference, we interviewed a series of invited speakers on the benefits of physical activity for cancer prevention and treatment and asked speakers to share some of the key scientific advances in exercise oncology.

Watch the video and hear what they had to say — we hope you enjoy it!

This recognition affirms the dedication and collaborative effort of countless individuals over the years in building the diverse and sophisticated infrastructure necessary to support a world-class, cutting-edge biomedical research centre.

A New Player in Pancreatic Cancer

The team found that some pancreatic cancer cells gain a major survival edge by carrying copies of critical cancer genes—such as MYC—on circular pieces of DNA that exist outside chromosomes, the structures that house most of our genetic material. Known as ecDNA, these genetic rings float freely in the cell nucleus, enabling tumour cells to swiftly ramp up gene expression, change their shape, and survive in otherwise hostile environments.